uvrC

uvrC
M129

locus
MPN125
function
DNA repair/ recombination
product
UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C)
MW
64460
pI
9.52
Gene length
1761 bp Sequence Blast
Protein length
586 aa Sequence Blast
essential
conditional essential

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0322

This gene is a member of the following regulons

gene
coordinates
161817 → 163577 (+)
phenotypes of a KO
growth defects and was exquisitely sensitive to DNA damage in M.genitalium [pubmed|31445891]
the protein
localization
cytoplasm, excinuclease repair complex (according to UniProt)
structure
[PDB|1YD6] from Bacillus caldotenax, corresponds to the N-Terminal (aa 4 - 63, 64 - 102) (46% identity) [pubmed|15692561]
[PDB|3C65] from Geobacillus stearothermophilus, corresponds to the C-Terminal (aa 377 - 580) (29% identity)
[AF|P75350]
references
reviews
16464004,15927210,7801120
original publications
15692561,22686427,31445891

1048c5083ff88b5495b4190be9612f3669951067

Page visits: 304

Time of last update: 2024-05-10 20:55:04

Author of last update: Jstuelk