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R21: D-fructose[e] + protein N(pi)-phospho-L-histidine = D-fructose 1-phosphate + protein L-histidine
D-fructose 1-phosphate
protein L-histidine
D-fructose[e]
protein N(pi)-phospho-L-histidine
FruA
R1: protein L-histidine + phosphoenolpyruvate = protein N(pi)-phospho-L-histidine + pyruvate
protein N(pi)-phospho-L-histidine
pyruvate
protein L-histidine
phosphoenolpyruvate
PtsI
R23: D-fructose 1-phosphate = glycerone phosphate + D-glyceraldehyde
glycerone phosphate
D-glyceraldehyde
D-fructose 1-phosphate
Fba
R24: D-glyceraldehyde + NADH + H+ = D-glycerol + NAD+
D-glycerol
NAD
+
H
+
D-glyceraldehyde
NADH
Adh
R192: D-glycerol [e] = D-glycerol
D-glycerol
D-glycerol [e]
GlpF
R49: D-glycerol + ATP = ADP + D-glycerol 3-phosphate
ADP
D-glycerol 3-phosphate
ATP
D-glycerol
GlpK
R186: 2 D-glycerol 3-phosphate + O2 = 2 glycerone phosphate + H2O2
glycerone phosphate
H
2
O
2
D-glycerol 3-phosphate
O
2
GlpO
R206: O2[e] = O2
O
2
O
2
[e]
R211: H2O2[e] = H2O2
H
2
O
2
H
2
O
2
[e]
R53: acyl-[acyl-carrier protein] + sn-glycerol 3-phosphate = [acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate
1-acyl-sn-glycerol 3-phosphate
[acyl-carrier protein]
D-glycerol 3-phosphate
acyl-[acyl-carrier protein]
PlsY
R54: acyl-[acyl-carrier protein] + 1-acyl-sn-glycerol 3-phosphate = [acyl-carrier protein] + 1,2-diacyl-sn-glycerol 3-phosphate
1,2-diacyl-sn-glycerol 3-phosphate
[acyl-carrier protein]
acyl-[acyl-carrier protein]
1-acyl-sn-glycerol 3-phosphate
PlsC
R452: 1,2-diacyl-sn-glycerol 3-phosphate + CTP <=> CDP-diacylglycerol + diphosphate
CDP-diacylglycerol
diphosphate
CTP
1,2-diacyl-sn-glycerol 3-phosphate
CdsA
R56: CDP-diacylglycerol + D-glycerol 3-phosphate = 3(3-phosphatidyl-)L-glycerol 1-phosphate + CMP
3(3-phosphatidyl-)L-glycerol 1-phosphate
CMP
D-glycerol 3-phosphate
CDP-diacylglycerol
PgsA
R57: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate
phosphate
phosphatidylglycerol
H
2
O
3(3-phosphatidyl-)L-glycerol 1-phosphate
R58: phosphatidylglycerol + CDP-diacylglycerol = cardiolipin + CMP
CMP
cardiolipin
CDP-diacylglycerol
phosphatidylglycerol
R59: phosphatidate + H2O = 1,2-diacyl-sn-glycerol + phosphate
phosphate
1,2-diacyl-sn-glycerol
H
2
O
1,2-diacyl-sn-glycerol 3-phosphate
Lip3
R64: UDP-galactose + 1,2-diacyl-sn-glycerol = UDP + D-galactosyl-1,2-diacylglycerol
UDP
D-galactosyl-1,2-diacylglycerol
UDP-galactose
1,2-diacyl-sn-glycerol
YibD
R428: L-1,2-diacylglycerol + UDP-glucose = D-glucosyl-1,2-diacylglycerol + UDP
UDP
D-glucosyl-1,2-diacylglycerol
UDP-glucose
1,2-diacyl-sn-glycerol
YibD
R2: D-glucose[e] + protein N(pi)-phospho-L-histidine = D-glucose 6-phosphate + protein L-histidine
D-glucose 6-phosphate
protein L-histidine
protein N(pi)-phospho-L-histidine
D-glucose[e]
PtsG
R1: protein L-histidine + phosphoenolpyruvate = protein N(pi)-phospho-L-histidine + pyruvate
protein N(pi)-phospho-L-histidine
pyruvate
protein L-histidine
phosphoenolpyruvate
PtsI
R60: D-glucose 1-phosphate = D-glucose 6-phosphate
D-glucose 6-phosphate
D-glucose 1-phosphate
CpsG
R61: D-glucose 1-phosphate + UTP = UDP-glucose + PPi
UDP-glucose
D-glucose 1-phosphate
UTP
GtaB
R62: UDP-glucose = UDP-galactose
UDP-galactose
UDP-glucose
GalE
R3: D-glucose 6-phosphate = D-fructose 6-phosphate
D-fructose 6-phosphate
D-glucose 6-phosphate
PgiB
R26: D-mannose[e] + protein N(pi)-phospho-L-histidine = D-mannose 6-phosphate + protein L-histidine
D-mannose 6-phosphate
protein L-histidine
protein N(pi)-phospho-L-histidine
D-mannose[e]
FruA
R1: protein L-histidine + phosphoenolpyruvate = protein N(pi)-phospho-L-histidine + pyruvate
protein N(pi)-phospho-L-histidine
pyruvate
protein L-histidine
phosphoenolpyruvate
PtsI
R28: D-mannose 6-phosphate = D-fructose 6-phosphate
D-fructose 6-phosphate
D-mannose 6-phosphate
R27: D-mannose 1-phosphate = D-mannose 6-phosphate
D-mannose 6-phosphate
D-mannose 1-phosphate
CpsG
R4: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate
ADP
D-fructose 1,6-bisphosphate
ATP
D-fructose 6-phosphate
Pfk
R5: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
glycerone phosphate
D-glyceraldehyde 3-phosphate
D-fructose 1,6-bisphosphate
Fba
R6: D-glyceraldehyde 3-phosphate = glycerone phosphate
glycerone phosphate
D-glyceraldehyde 3-phosphate
TpiA
R7: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+
H
+
NADH
3-phospho-D-glyceroyl phosphate
phosphate
D-glyceraldehyde 3-phosphate
NAD
+
Gap
R8: 3-phospho-D-glyceroyl phosphate + ADP = 3-phospho-D-glycerate + ATP
ATP
3-phospho-D-glycerate
ADP
3-phospho-D-glyceroyl phosphate
Pgk
R9: 3-phospho-D-glycerate = 2-phospho-D-glycerate
2-phospho-D-glycerate
3-phospho-D-glycerate
Pgm
R10: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O
H
2
O
phosphoenolpyruvate
2-phospho-D-glycerate
Eno
R11: phosphoenolpyruvate + ADP = pyruvate + ATP
ATP
pyruvate
ADP
phosphoenolpyruvate
Pyk
R15: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2
CO
2
S-acetyldihydrolipoamide
pyruvate
lipoamide
PdhA
R16: S-acetyldihydrolipoamide + CoA = dihydrolipoamide + acetyl-CoA
dihydrolipoamide
acetyl-CoA
CoA
S-acetyldihydrolipoamide
PdhC
R17: dihydrolipoamide + NAD+ = lipoamide + NADH + H+
H
+
NADH
lipoamide
NAD
+
dihydrolipoamide
PdhD
R12: pyruvate + NADH + H+ = (S)-lactate + NAD+
NAD
+
(S)-lactate
H
+
NADH
pyruvate
Ldh
R430: phosphatidylcholine[e] + H2O + ATP = phosphatidylcholine + ADP + Pi + H+
ADP
H
+
phosphatidylcholine
Pi
ATP
H
2
O
phosphatidylcholine[e]
R187: phosphatidylcholine + 2 H2O = glycerophosphocholine + 2 fatty acid
glycerophosphocholine
fatty acid
H
2
O
phosphatidylcholine
Lip3
R182: glycerophosphocholine + H2O = choline + D-glycerol 3-phosphate
D-glycerol 3-phosphate
choline
H
2
O
glycerophosphocholine
GlpQ
R178: choline + ATP = choline phosphate + ADP
ADP
choline phosphate
ATP
choline
LicA
R180: choline phosphate + CTP = CDP-choline + pyrophosphate
CDP-choline
pyrophosphate
CTP
choline phosphate
NadD
R218: pantetheine[e] = pantetheine
pantetheine
pantetheine[e]
R145: pantetheine + ATP = pantetheine 4'-phosphate + ADP
ADP
pantetheine 4'-phosphate
ATP
pantetheine
R146: pantetheine 4'-phosphate + ATP = dephospho-CoA + PPi
PPi
dephospho-CoA
ATP
pantetheine 4'-phosphate
NadD
R147: dephospho-CoA + ATP = CoA + ADP
ADP
CoA
ATP
dephospho-CoA
CoaE
R149: holo-[acyl-carrier protein] + H2O = pantetheine 4'-phosphate + apo-[acyl-carrier protein]
apo-[acyl-carrier protein]
pantetheine 4'-phosphate
H
2
O
holo-[acyl-carrier protein]
AcpH
R148: apo-[acyl-carrier protein] + CoA= holo-[acyl-carrier protein] + adenosine 3',5'-bisphosphate
holo-[acyl-carrier protein]
adenosine 3',5'-bisphosphate
apo-[acyl-carrier protein]
CoA
AcpS
R150: fatty acid + holo-[acyl-carrier protein] + ATP = acyl-[acyl-carrier protein] + AMP + PPi
AMP
PPi
acyl-[acyl-carrier protein]
holo-[acyl-carrier protein]
fatty acid
R188: adenosine 3',5'-bisphosphate + H2O = AMP + phosphate
AMP
phosphate
H
2
O
adenosine 3',5'-bisphosphate
R267: phosphate --> phosphate[e]
phosphate[e]
phosphate
R453: phosphate[e] + ATP + H2O = H+ + ADP + phosphate
ADP
phosphate
H+
ATP
phosphate[e]
H2O
Phosphate transport system
PhoU
PstB
PstA
PstS
R217: nicotinate[e] = nicotinate
nicotinate
nicotinate[e]
R136: nicotinate + 5-phospho-D-ribose 1-PPi = nicotinate D-ribonucleotide + PPi
PPi
nicotinate D-ribonucleotide
5-phospho-D-ribose 1-PPi
nicotinate
PncB
R137: nicotinate D-ribonucleotide + ATP = deamido-NAD+ + PPi
PPi
deamido-NAD
+
ATP
nicotinate D-ribonucleotide
NadD
R138: deamido-NAD+ + ATP + NH3 = NAD+ + AMP + PPi
AMP
PPi
NAD
+
ATP
NH
3
deamido-NAD
+
OutB
R139: NAD+ + ATP = NADP+ + ADP
ADP
NADP
+
ATP
NAD
+
PpnK
R213: folate[e] = folate
folate
folate[e]
R194: folate + NADH + H+ = dihydrofolate + NAD+
NAD
+
dihydrofolate
H
+
NADH
folate
Dhfr
Dyr
R126: dihydrofolate + NADH + H+ = tetrahydrofolate + NAD+
tetrahydrofolate
NAD
+
H
+
NADH
dihydrofolate
Dhfr
R127: tetrahydrofolate + formate + ATP = 10-formyltetrahydrofolate + ADP + phosphate
ADP
10-formyltetrahydrofolate
phosphate
ATP
tetrahydrofolate
formate
Mtd1
R129: L-methionyl-tRNAfMet + 10-formyltetrahydrofolate + H2O = N-formylmethionyl-tRNAfMet + tetrahydrofolate
tetrahydrofolate
N-formylmethionyl-tRNAfMet
10-formyltetrahydrofolate
H
2
O
L-methionyl-tRNAfMet
Fmt
R128: 10-formyltetrahydrofolate + H+ = 5,10-methenyltetrahydrofolate + H2O
5,10-methenyltetrahydrofolate
H
2
O
10-formyltetrahydrofolate
H
+
Mtd1
R130: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine
L-serine
tetrahydrofolate
H
2
O
5,10-methylenetetrahydrofolate
glycine
GlyA
R131: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
H
+
5,10-methenyltetrahydrofolate
NADPH
5,10-methylenetetrahydrofolate
NADP
+
Mtd1
R431: dUMP + 5,10-methylenetetrahydrofolate = dTMP + dihydrofolate
dTMP
dihydrofolate
dUMP
5,10-methylenetetrahydrofolate
ThyA
R226: acetate + H+[e] = acetate[e] + H+[e]
H
+
acetate
H
+
[e]
acetate[e]
R19: acetyl phosphate + ADP = acetate + ATP
ATP
acetate
ADP
acetyl phosphate
AckA
R18: acetyl-CoA + phosphate = CoA + acetyl phosphate
CoA
acetyl phosphate
phosphate
acetyl-CoA
Pta
R47: acetyl-CoA + NADH + H+ = acetaldehyde + CoA + NAD+
acetaldehyde
CoA
H
+
NADH
acetyl-CoA
Adh
R48: acetaldehyde + NADH + H+ = ethanol + NAD+
NAD
+
ethanol
H
+
acetaldehyde
NADH
Adh
R46: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
D-glyceraldehyde 3-phosphate
acetaldehyde
2-deoxy-D-ribose 5-phosphate
DeoC
R44: 2-deoxy-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate
2-deoxy-D-ribose 5-phosphate
2-deoxy-D-ribose 1-phosphate
CpsG
R29: D-mannitol[e] + protein N(pi)-phospho-L-histidine = D-mannitol 1-phosphate + protein L-histidine
protein L-histidine
D-mannitol 1-phosphate
protein N(pi)-phospho-L-histidine
D-mannitol[e]
MtlF
R1: protein L-histidine + phosphoenolpyruvate = protein N(pi)-phospho-L-histidine + pyruvate
protein N(pi)-phospho-L-histidine
pyruvate
protein L-histidine
phosphoenolpyruvate
PtsI
R30: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+
H
+
D-fructose 6-phosphate
NADH
NAD
+
D-mannitol 1-phosphate
MtlD
R191: D-ribose[e] + ATP + H2O = D-ribose + ADP + phosphate
ADP
phosphate
D-ribose
ATP
H
2
O
D-ribose[e]
R36: D-ribose + ATP = D-ribose 5-phosphate + ADP
ADP
D-ribose 5-phosphate
ATP
D-ribose
R43: D-ribose 1-phosphate = D-ribose 5-phosphate
D-ribose 5-phosphate
D-ribose 1-phosphate
CpsG
R39: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
D-ribose 5-phosphate
D-xylulose 5-phosphate
D-glyceraldehyde 3-phosphate
D-sedoheptulose 7-phosphate
TklB
R38: D-erythrose 4-phosphate + D-fructose 6-phosphate = D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
D-glyceraldehyde 3-phosphate
D-sedoheptulose 7-phosphate
D-fructose 6-phosphate
D-erythrose 4-phosphate
R37: D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate = D-xylulose 5-phosphate + D-erythrose 4-phosphate
D-xylulose 5-phosphate
D-erythrose 4-phosphate
D-glyceraldehyde 3-phosphate
D-fructose 6-phosphate
TklB
R7: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+
H
+
NADH
3-phospho-D-glyceroyl phosphate
phosphate
D-glyceraldehyde 3-phosphate
NAD
+
Gap
R8: 3-phospho-D-glyceroyl phosphate + ADP = 3-phospho-D-glycerate + ATP
ATP
3-phospho-D-glycerate
ADP
3-phospho-D-glyceroyl phosphate
Pgk
R9: 3-phospho-D-glycerate = 2-phospho-D-glycerate
2-phospho-D-glycerate
3-phospho-D-glycerate
Pgm
R10: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O
H
2
O
phosphoenolpyruvate
2-phospho-D-glycerate
Eno
R11: phosphoenolpyruvate + ADP = pyruvate + ATP
ATP
pyruvate
ADP
phosphoenolpyruvate
Pyk
R40: D-ribulose 5-phosphate = D-xylulose 5-phosphate
D-xylulose 5-phosphate
D-ribulose 5-phosphate
CfxE
R41: D-ribose 5-phosphate = D-ribulose 5-phosphate
D-ribulose 5-phosphate
D-ribose 5-phosphate
RpiB
R42: D-ribose 5-phosphate + ATP = 5-phospho-D-ribose 1-PPi + AMP
AMP
5-phospho-D-ribose 1-PPi
ATP
D-ribose 5-phosphate
Prs
R31: L-ascorbate[e] + protein N(pi)-phospho-L-histidine = L-ascorbate 6-phosphate + protein L-histidine
protein L-histidine
L-ascorbate 6-phosphate
protein N(pi)-phospho-L-histidine
L-ascorbate[e]
UlaA
R1: protein L-histidine + phosphoenolpyruvate = protein N(pi)-phospho-L-histidine + pyruvate
protein N(pi)-phospho-L-histidine
pyruvate
protein L-histidine
phosphoenolpyruvate
PtsI
R32: L-ascorbate 6-phosphate + H2O = 3-dehydro-L-gulonate 6-phosphate
3-dehydro-L-gulonate 6-phosphate
H
2
O
L-ascorbate 6-phosphate
UlaG
R33: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2
CO
2
L-xylulose 5-phosphate
H
+
3-dehydro-L-gulonate 6-phosphate
UlaD
R34: L-ribulose 5-phosphate = L-xylulose 5-phosphate
L-xylulose 5-phosphate
L-ribulose 5-phosphate
UlaE
R35: L-ribulose 5-phosphate = D-xylulose 5-phosphate
D-xylulose 5-phosphate
L-ribulose 5-phosphate
AraD
R216: adenine + H+ = adenine[e] + H+[e]
H
+
adenine
H
+
[e]
adenine[e]
R66: adenosine + phosphate = adenine + D-ribose 1-phosphate
adenine
D-ribose 1-phosphate
phosphate
adenosine
DeoD
R67: AMP + H2O = adenosine + phosphate
phosphate
adenosine
AMP
H
2
O
R68: AMP + ATP = 2 ADP
ADP
ATP
AMP
Adk
R11: phosphoenolpyruvate + ADP = pyruvate + ATP
ATP
pyruvate
ADP
phosphoenolpyruvate
Pyk
R71: RNAn + NTP = RNAn+1 + PPi
PPi
RNA(n+1)
ATP
RNA(n)
MPN191;MPN515;MPN516;MPN352
RpoA
RpoC
RpoB
SigA
R73: deoxyadenosine + phosphate = adenine + 2-deoxy-D-ribose 1-phosphate
adenine
2-deoxy-D-ribose 1-phosphate
phosphate
deoxyadenosine
DeoD
R74: deoxyadenosine + ATP = dAMP + ADP
ADP
dAMP
ATP
deoxyadenosine
YaaF
R75: dAMP + ATP = dADP + ADP
ADP
dADP
ATP
dAMP
Adk
R76: phosphoenolpyruvate + dADP = pyruvate + dATP
dATP
pyruvate
dADP
phosphoenolpyruvate
Pyk
R454: DNA(n) + dATP = PPi + DNA(n+1)
PPi
DNA(n+1)
dATP
DNA(n)
PolC
R455: ADP + txrB-(R'-SH)
2
= dADP + txrB-R'-S-S-R' + H
2
O
H
2
O
dADP
txrB-R'-S-S-R'
ADP
txrB-(R'-SH)
2
Ribonucleoside-diphosphate reductase
NrdF
NrdI
NrdE
R65: adenine + 5-phospho-D-ribose 1-PPi = AMP + PPi
AMP
PPi
5-phospho-D-ribose 1-PPi
adenine
Apt
R210: guanine[e] + H+[e] = guanine + H+
H
+
guanine
H
+
[e]
guanine[e]
R79: guanosine + phosphate = guanine + D-ribose 1-phosphate
D-ribose 1-phosphate
guanine
phosphate
guanosine
DeoD
R80: GMP + H2O = guanosine + phosphate
phosphate
guanosine
H
2
O
GMP
R81: GMP + ATP = GDP + ADP
ADP
GDP
ATP
GMP
Gmk
R83: phosphoenolpyruvate + GDP = pyruvate + GTP
pyruvate
GTP
GDP
phosphoenolpyruvate
Pyk
R456: RNA(n) + GTP = RNA(n+1) + PPi
PPi
RNA(n+1)
GTP
RNA(n)
RpoB
R85: deoxyguanosine + phosphate = guanine + 2-deoxy-D-ribose 1-phosphate
2-deoxy-D-ribose 1-phosphate
guanine
phosphate
deoxyguanosine
DeoD
R86: deoxyguanosine + ATP = dGMP + ADP
ADP
dGMP
ATP
deoxyguanosine
YaaF
R87: dGMP + ATP = dGDP + ADP
ADP
dGDP
ATP
dGMP
Gmk
R88: phosphoenolpyruvate + dGDP = pyruvate + dGTP
pyruvate
dGTP
dGDP
phosphoenolpyruvate
Pyk
R457: DNA(n) + dGTP = DNA(n+1) + PPi
PPi
DNA(n+1)
dGTP
DNA(n)
R78: guanine + 5-phospho-D-ribose 1-PPi = GMP + PPi
PPi
GMP
5-phospho-D-ribose 1-PPi
guanine
Hpt
R458: GDP + txrB-R'-S-S-R' = dGDP + H
2
O + OsmC-R'-S-S-R'
H
2
O
dGDP
OsmC-R'-S-S-R'
txrB-R'-S-S-R'
GDP
NrdF
R202: uracil[e] + H+[e]= uracil + H+
H
+
uracil
H
+
[e]
uracil[e]
R459: uracil + D-ribose 1-phosphate <=> uridine + phosphate
phosphate
uridine
uracil
D-ribose 1-phosphate
DeoA
R111: phosphate + deoxyuridine <=> uracil + 2-deoxy-D-ribose 1-phosphate
uracil
2-deoxy-D-ribose 1-phosphate
phosphate
deoxyuridine
DeoA
R113: dUMP + H2O = deoxyuridine + phosphate
phosphate
deoxyuridine
dUMP
H
2
O
R112: deoxyuridine + ATP = dUMP + ADP
dUMP
ADP
ATP
deoxyuridine
Tdk
R189: dUMP + ATP = dUDP + ADP
dUDP
ADP
ATP
dUMP
Tmk
R93: Uridine + ATP = UMP + ADP
ADP
UMP
ATP
uridine
Udk
R92: UMP + H2O = uridine + phosphate
phosphate
uridine
H
2
O
UMP
R94: UMP + ATP = UDP + ADP
ADP
UDP
ATP
UMP
PyrH
R460: txrB-R'-S-S-R' + H
2
O + dUDP <=> UDP + txrB-(R'-SH)
2
UDP
txrB-(R'-SH)
2
dUDP
H
2
O
txrB-R'-S-S-R'
NrdF
R95: phosphoenolpyruvate + UDP = pyruvate + UTP
UTP
pyruvate
phosphoenolpyruvate
UDP
Pyk
R461: RNA(n) + UTP <=> RNA(n+1) + PPi
PPi
RNA(n+1)
UTP
RNA(n)
RpoB
R462: RNA(n+1) + H
2
O = UMP + RNA(n)
UMP
RNA(n)
H
2
O
RNA(n+1)
R90: uracil + 5-phospho-D-ribose 1-PPi = UMP + PPi
PPi
UMP
uracil
5-phospho-D-ribose 1-PPi
Upp
R247: deoxycytidine[e] + H+[e] = deoxycytidine + H+
H
+
deoxycytidine
H
+
[e]
deoxycytidine[e]
R106: deoxycytidine + ATP = dCMP + ADP
ADP
dCMP
ATP
deoxycytidine
YaaF
R107: dCMP + H2O = deoxycytidine + phosphate
phosphate
deoxycytidine
H
2
O
dCMP
R208: cytidine[e] + H+[e] = cytidine + H+
H
+
cytidine
cytidine[e]
H
+
[e]
R100: cytidine + ATP = CMP + ADP
ADP
CMP
ATP
cytidine
Udk
R101: CMP + H2O = cytidine + phosphate
phosphate
cytidine
H
2
O
CMP
R102: CMP + ATP = CDP + H2O
CDP
ATP
CMP
Cmk
R108: dCMP + ATP = dCDP + ADP
ADP
dCDP
ATP
dCMP
Cmk
R463: CDP + txrB-(R'-SH)
2
= dCDP + txrB-R'-S-S-R' + H
2
O
H
2
O
txrB-R'-S-S-R'
dCDP
CDP
txrB-(R'-SH)
2
R109: phosphoenolpyruvate + dCDP = pyruvate + dCTP
pyruvate
dCTP
phosphoenolpyruvate
dCDP
Pyk
R464: dCTP + DNA(n) = DNA(n+1) + PPi
PPi
DNA(n+1)
dCTP
DNA(n)
PolC
R103: phosphoenolpyruvate + CDP = pyruvate + CTP
CTP
pyruvate
phosphoenolpyruvate
CDP
Pyk
R465: CTP + RNA(n) <=> PPi + RNA(n+1)
PPi
RNA(n+1)
CTP
RNA(n)
RpoB
R467: RNA(n+1) + H
2
O = RNA(n) + CMP
CMP
RNA(n)
H
2
O
RNA(n+1)
R98: UTP + ATP + NH3 = CTP + ADP + phosphate
ADP
phosphate
CTP
ATP
NH
3
UTP
Mpn256
R72: PPi + H2O = Pi + Pi
phosphate
PPi
H
2
O
Ppa
R203: thymine[e] + H+[e] = thymine + H+
H
+
thymine
H
+
[e]
thymine[e]
R115: thymidine + phosphate = thymine + 2-deoxyD-ribose 1-phosphate
2-deoxy-D-ribose 1-phosphate
thymine
phosphate
thymidine
DeoA
R116: thymidine + ATP = dTMP + ADP
ADP
dTMP
ATP
thymidine
Tdk
R468: dTMP + H
2
O = phosphate + thymidine
phosphate
thymidine
dTMP
H
2
O
R118: dTMP + ATP = dTDP + ADP
ADP
dTDP
ATP
dTMP
Tmk
R119: phosphoenolpyruvate + dTDP = pyruvate + dTTP
pyruvate
dTTP
dTDP
phosphoenolpyruvate
Pyk
R469: dTTP + DNA(n) = DNA(n+1) + PPi
PPi
DNA(n+1)
dTTP
DNA(n)
PolC
R431: dUMP + 5,10-methylenetetrahydrofolate = dTMP + dihydrofolate
dTMP
dihydrofolate
dUMP
5,10-methylenetetrahydrofolate
ThyA
R212: pyridoxal[e] = pyridoxal
pyridoxal
pyridoxal[e]
R142: pyridoxal + ATP = pyridoxal 5'-phosphate + ADP
ADP
pyridoxal 5'-phosphate
ATP
pyridoxal
R470: thiamine[e] + ATP + H2O = H+ + phosphate + ADP + thiamine
ADP
phosphate
thiamine
H+
ATP
thiamine[e]
H2O
R143: thiamine + ATP = thiamine phosphate + ADP
ADP
thiamine phosphate
ATP
thiamine
R144: thiamine phosphate + ATP = thiamine PPi + ADP
ADP
thiamine PPi
ATP
thiamine phosphate
ThiI
R207: riboflavin[e] = riboflavin
riboflavin
riboflavin[e]
R140: riboflavin + ATP = FMN + ADP
ADP
FMN
ATP
riboflavin
YaaC
R141: FMN + ATP = FAD + PPi
PPi
FAD
ATP
FMN
YaaC
R229: L-asparagine + H+ = L-asparagine[e] + H+[e]
H
+
L-asparagine
H
+
[e]
L-asparagine[e]
R257: L-glutamine[e] + H2O + ATP --> L-glutamine + ADP + phosphate + H+
ADP
H
+
phosphate
L-glutamine
ATP
H
2
O
L-glutamine[e]
GlnQ
R233: L-glutamine + H+ = L-glutamine[e] + H+[e]
H
+
[e]
L-glutamine[e]
H
+
L-glutamine
R152: glutamyl-tRNA(Gln) + L-glutamine + ATP = glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate
ADP
phosphate
glutaminyl-tRNA(Gln)
L-glutamate
ATP
glutamyl-tRNA(Gln)
L-glutamine
MPN236;MPN237;MPN238
GatC
GatA
GatB
R151: glutamyl-tRNA(Gln) + L-asparagine + ATP = glutaminyl-tRNA(Gln) + L-aspartate + ADP + phosphate
ADP
phosphate
L-aspartate
glutaminyl-tRNA(Gln)
ATP
glutamyl-tRNA(Gln)
L-asparagine
MPN236;MPN237;MPN238
GatC
GatA
GatB
R432: Amino acid[e] + ATP + H2O = Amino acid + ADP + Pi + H+
ADP
H
+
Pi
amino acid
ATP
H
2
O
amino acid[e]
R471: amino acid + tRNA + ATP = PPi + AMP + aa-tRNA
AMP
PPi
aa-tRNA
ATP
amino acid