asnS

asnS
M129

locus
MPN252
function
tRNA synthases
product
Asparaginyl-tRNA synthetase (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS)
MW
50050
ec
6.1.1.22
pI
8.87
Gene length
1368 bp Sequence Blast
Protein length
455 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0017

This gene is a member of the following regulons

gene
coordinates
303037 → 304404 (+)
phenotypes of an overexpression
fast growth [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
L-asparagine + tRNA(Asn) + ATP = L-asparaginyl-tRNA(Asn) + AMP + PPi, reversible reaction
localization
cytoplasm (according to UniProt)
modification
Acetylated in Lysine, at K112 [pubmed|22373819]
structure
[PDB|6PQH], from Elizabethkingia sp., Crystal structure of asparaginyl-tRNA synthetase complexed with asparaginyl-adenylate (40% identity) [pubmed|16753178]
[AF|P75521]
references
16753178,31445891,22373819

223871e522588d5b24fedab2e967fba78ae13c5a

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Time of last update: 2025-09-23 02:29:15

Author of last update: Jstuelk