acpS
M129
locus
MPN298
function
Lipid/CoA metabolism
product
Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (EC 2.7.8.7) (4'-phosphopantetheinyl transferase acpS)
MW
13090
ec
2.7.8.7
pI
9.69
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
352387 → 352746 (+)
the protein
catalyzed reaction/ biological activity
apo-[acyl-carrier protein] + CoA= holo-[acyl-carrier protein] + adenosine 3',5'-bisphosphate, reversible reaction. ACP (acyl carrier protein) is MPN406
localization
cytoplasm (according to UniProt)
cofactors
Mg2+
structure
[PDB|5VBX], from Escherichia coli, Crystal structure of holo-[acyl-carrier-protein] synthase (AcpS) (35% identity) [pubmed|29054754]
[AF|P75480]
expression and Regulation
other regulations
expression is altered upon depletion of the [protein|84ec337a1f299161ee8f9778847bccbd3f07534d|Lon] protease [pubmed|33320415]
references
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Time of last update: 2024-04-29 07:38:37
Author of last update: Jstuelk