yacA
M129

locus

MPN222

function

tRNA modifications/processing

product

tRNA(Ile)-lysidine synthase (EC 6.3.4.-) (tRNA(Ile)-lysidine synthetase) (tRNA(Ile)-2-lysyl-cytidine synthase)

31790

6.3.4.-

synonyms

tilS

Gene length

870 bp Sequence Blast

Protein length

289 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0037

This gene is a member of the following regulons

gene

coordinates

273701 → 274570 (+)

the protein

catalyzed reaction/ biological activity

[tRNAIle2]-cytidine34 + L-lysine + ATP = [tRNAIle2]-lysidine34 + AMP + PPi + H2O, reversible reaction

localization

cytoplasm (according to UniProt)

structure

[PDB|3A2K] from Geobacillus kaustophilus, Crystal structure of TilS complexed with tRNA (25% identity) [pubmed|19847269]

[AF|P75549]

references

reviews

15124629,19944692

original publications

14527414,19233850,19847269

Page visits: 244

Time of last update: 2025-04-16 14:55:47

Author of last update: Jstuelk