hepA
M129
similar to SNF2 helicase
locus
MPN020
function
DNA synthesis/modifications/repair/conformation
product
Uncharacterized ATP-dependent helicase (EC 3.6.1.-)
MW
113300
ec
3.6.1.-
pI
8.34
synonyms
HepA,RapA, YabA
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
23022 → 26114 (+)
phenotypes of an overexpression
Slow acidification [pubmed|31445891]
20 genes changing [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
HepA + ATP + RNApol = HepA-RNApol + ADP + Pi, reversible reaction
localization
cytoplasm
modification
Acetylated in Lysine, at K260 [pubmed|22373819]
Acetylated in Lysine, at K793 [pubmed|22373819]
Acetylated in Lysine, at K765 [pubmed|22373819]
Acetylated in Lysine, at K350 [pubmed|22373819]
Acetylated in Lysine, at K923 [pubmed|22373819]
Acetylated in Lysine, at K252 [pubmed|22373819]
Phosphorylated in Ser/Thr, at S48 [pubmed|22373819]
structure
[PDB|1Z6A] from Sulfolobus solfataricus, the C-terminal domain (39% identity) [pubmed|15882619]
[AF|P75093]
references
original publications
Page visits: 317
Time of last update: 2024-05-02 13:16:26
Author of last update: Jstuelk