gap
M129
locus
MPN430
function
Glycolysis
product
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12)
MW
37070
ec
1.2.1.12
pI
8.94
synonyms
gapA
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
518850 → 517837 (-)
the protein
catalyzed reaction/ biological activity
D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+, reversible reaction
localization
cytoplasm (according to UniProt)
membrane [pubmed|26667841]
modification
Acetylated in Lysine, at K143 [pubmed|22373819]
Acetylated in Lysine, at K219 [pubmed|22373819]
Acetylated in Lysine, at K66 [pubmed|22373819]
Acetylated in Lysine, at K60 [pubmed|22373819]
Acetylated in Lysine, at K74 [pubmed|22373819]
Acetylated in Lysine, at K74 [pubmed|22373819]
Acetylated in Lysine, at K267 [pubmed|22373819]
Acetylated in Lysine, at K62 [pubmed|22373819]
Phosphorylated in Ser/Thr, at T213/ T214/ T215, by [protein|f509c1e951bb17604c3bfcd5af69fb9655916c48|PrkC] [pubmed|22373819]
Phosphorylated in Ser/Thr, at LQDAPHpSDLR [pubmed|22373819]
Phosphorylated in Ser/Thr, at T229 [pubmed|22373819]
Phosphorylated in Ser/Thr, at IISAASCpTTNCLAPMVHVLEK [pubmed|22373819]
structure
[PDB|5UTL], from Streptococcus agalactiae, Mutant Structures GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (55% identity)
[AF|P75358]
references
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Time of last update: 2025-06-03 12:47:59
Author of last update: Jstuelk