parE
M129
locus
MPN122
function
chromosome segregation and compaction
product
subunit of DNA topoisomerase IV
MW
69850
ec
5.99.1.-
pI
9.49
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
156467 → 158374 (+)
phenotypes of an overexpression
Slow acidification [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
a double stranded positively supercoiled DNA + ATP = relaxed double stranded DNA + ADP + Pi, reversible reaction
localization
chromosome (according to UniProt)
structure
[PDB|4I3H] the [protein|525c6dc24571fb58d491bef41af12c5efdf17642|ParE]-[protein|c6dc466d813dc45f428990be395f7addd6dffd57|ParC] complex of Streptococcus pneumoniae (49% identity) [pubmed|23965305]
[AF|P78016]
references
reviews
original publications
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Time of last update: 2024-04-28 21:15:53
Author of last update: Jstuelk