gyrA
M129

DNA gyrase (subunit A)

locus

MPN004

function

DNA supercoiling, control of replication initiation

product

DNA gyrase subunit A

92290

5.99.1.3

8.64

Gene length

2520 bp Sequence Blast

Protein length

839 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0188

This gene is a member of the following regulons

gene

coordinates

4821 → 7340 (+)

phenotypes of an overexpression

Slow growth [pubmed|31445891]

the protein

catalyzed reaction/ biological activity

dsDNA + ATP = negatively-supercoiled-dsDNA +ADP + Pi, reversible reaction

localization

cytoplasm, chromosome (according to UniProt)

modification

Acetylated in Lysine, at K736 [pubmed|22373819]

Acetylated in Lysine, at K286 [pubmed|22373819]

structure

[PDB|6RKS], from Escherichia coli, a DNA gyrase subunit (45% identity) [pubmed|31666516]

[AF|P22446]

references

reviews

16936698,29772727,33480441,33959387

original publications

31666516,32732422,31445891,22373819

Page visits: 428

Time of last update: 2025-07-27 03:10:14

Author of last update: Jstuelk