deoA
M129

thymidine phosphorylase

locus

MPN064

function

pyrimidine interconversion

product

thymidine phosphorylase

46310

2.4.2.4

9.38

Gene length

1266 bp Sequence Blast

Protein length

421 aa Sequence Blast

essential

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0213

This gene is a member of the following regulons

gene

coordinates

80414 → 81679 (+)

phenotypes of an overexpression

Fast growth [pubmed|31445891]

the protein

catalyzed reaction/ biological activity

thymidine + phosphate = thymine + 2-deoxyD-ribose 1-phosphate, reversible reaction

uridine + phosphate = uracil + D-ribose 1-phosphate (novel) , reversible reaction

deoxyuridine + phosphate = uracil + 2-deoxyD-ribose 1-phosphate (novel) , reversible reaction

localization

cytoplasm

structure

[PDB|5OLN] from Bacillus subtilis, X-Ray structure of the complex pyrimidine-nucleoside phosphorylase at 1.88 A (42% identity) [pubmed|29633966]

[AF|P75052]

references

29633966,32732422,31445891

Page visits: 371

Time of last update: 2024-04-18 17:52:43

Author of last update: Jstuelk