pgiB
M129
locus
MPN250
function
Glycolysis
product
Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)
MW
47300
ec
5.3.1.9
pI
9.45
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
301113 → 302405 (+)
the protein
catalyzed reaction/ biological activity
D-glucose 6-phosphate = D-fructose 6-phosphate, reversible reaction
localization
cytoplasm (according to UniProt)
modification
Acetylated in Lysine, at K24 [pubmed|22373819]
Acetylated in Lysine, at K107 [pubmed|22373819]
Acetylated in Lysine, at K426 [pubmed|22373819]
Acetylated in Lysine, at K4[pubmed|10770936]
Phosphorylated in Ser/Thr, at pSGRTLEPAVTFR [pubmed|22373819]
structure
[PDB|1B0Z], from Geobacillus stearothermophilus, The crystal structure of phosphoglucose isomerase-an enzyme with autocrine motility factor activity in tumor cells (37% identity) [pubmed|10770936]
[AF|P78033]
references
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Time of last update: 2025-08-01 13:43:48
Author of last update: Jstuelk