mnmE
M129
GTP-binding protein, putative tRNA modification GTPase
locus
MPN008
function
tRNA modification
product
putative tRNA modification GTPase mnmE
MW
48620
ec
3.6.-.-
pI
8.11
synonyms
thdF
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
9947 → 11275 (+)
the protein
catalyzed reaction/ biological activity
Exhibits a very high intrinsic GTPase hydrolysis rate (according to UniProt)
Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34 (according to UniProt)
localization
cytoplasm (according to UniProt)
structure
[PDB|1XZP] from ''Thermotoga maritima'', Structure of the GTP-binding protein TrmE (33% identity) [Pubmed|15616586]
[AF|P75104]
references
reviews
original publications
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Time of last update: 2025-05-17 20:59:32
Author of last update: Jstuelk