gyrB
M129

DNA gyrase (subunit B)

locus

MPN003

function

DNA supercoiling, control of replication initiation

product

DNA gyrase subunit B

71500

5.99.1.3

5.92

Gene length

1953 bp Sequence Blast

Protein length

650 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0187

This gene is a member of the following regulons

gene

coordinates

2869 → 4821 (+)

the protein

catalyzed reaction/ biological activity

dsDNA + ATP = negatively-supercoiled-dsDNA +ADP + Pi, reversible reaction

localization

cytoplasm, chromosome (according to UniProt)

modification

Acetylated in Lysine, at K579 [pubmed|22373819]

Acetylated in Lysine, at K308 [pubmed|22373819]

Phosphorylated in Ser/Thr, at S12, by [protein|f509c1e951bb17604c3bfcd5af69fb9655916c48|PrkC] [pubmed|22373819]

structure

[PDB|6GAU], from Mycobacterium tuberculosis, a DNA gyrase subunit (48% identity) [pubmed|30744994]

[AF|P22447]

references

reviews

16936698,29772727,33480441,33959387

original publications

30744994,32732422,22373819

Page visits: 263

Time of last update: 2025-05-09 17:50:04

Author of last update: Jstuelk