gatC

gatC
M129

membrane protein, the C-terminal domain is similar to GatC

locus
MPN236
function
tRNA synthases
product
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (Asp/Glu-ADT subunit C) (EC 6.3.5.-)
MW
52690
ec
6.3.5.7
pI
10.14
Gene length
1440 bp Sequence Blast
Protein length
479 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0721

This gene is a member of the following regulons

gene
coordinates
287388 → 288827 (+)
the protein
catalyzed reaction/ biological activity
glutamyl-tRNA(Gln) + L-asparagine + ATP = glutaminyl-tRNA(Gln) + L-aspartate + ADP + phosphate, reversible reaction. In systems lacking discernible glutamine---tRNA ligase (EC 6.1.1.8), glutaminyl-tRNAGln is formed by a two-enzyme system. In the first step, a nondiscriminating ligase (EC 6.1.1.24 glutamate---tRNAGln ligase) mischarges tRNAGln with glutamate, forming glutamyl-tRNAGln. The glutamyl-tRNAGln is not used in protein synthesis until the present enzyme converts it into glutaminyl-tRNAGln (glutamyl-tRNAGlu is not a substrate for this reaction).
localization
cell membrane, multi-pass membrane protein, integral component of membrane (according to UniProt)
structure
[AF|P75535]
references
32732422,9342321,20882017,16809541

7ea128a0f08ab1d88b0cb51ecc0137620631ce44

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Time of last update: 2024-03-28 06:15:02

Author of last update: Jstuelk