gatC
M129
membrane protein, the C-terminal domain is similar to GatC
locus
MPN236
function
tRNA synthases
product
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (Asp/Glu-ADT subunit C) (EC 6.3.5.-)
MW
52690
ec
6.3.5.7
pI
10.14
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
287388 → 288827 (+)
the protein
catalyzed reaction/ biological activity
glutamyl-tRNA(Gln) + L-asparagine + ATP = glutaminyl-tRNA(Gln) + L-aspartate + ADP + phosphate, reversible reaction. In systems lacking discernible glutamine---tRNA ligase (EC 6.1.1.8), glutaminyl-tRNAGln is formed by a two-enzyme system. In the first step, a nondiscriminating ligase (EC 6.1.1.24 glutamate---tRNAGln ligase) mischarges tRNAGln with glutamate, forming glutamyl-tRNAGln. The glutamyl-tRNAGln is not used in protein synthesis until the present enzyme converts it into glutaminyl-tRNAGln (glutamyl-tRNAGlu is not a substrate for this reaction).
localization
cell membrane, multi-pass membrane protein, integral component of membrane (according to UniProt)
structure
[AF|P75535]
references
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Time of last update: 2025-04-16 05:32:32
Author of last update: Jstuelk