hpt
M129

locus

MPN672

function

Nucleotide metabolism/Salvage

product

Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) (HGPRT) (EC 2.4.2.8)

20790

2.4.2.8

6.51

Gene length

570 bp Sequence Blast

Protein length

189 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0634

This gene is a member of the following regulons

gene

coordinates

797181 → 796612 (-)

the protein

catalyzed reaction/ biological activity

guanine + 5-phospho-D-ribose 1-PPi = GMP + PPi, reversible reaction

localization

cytoplasm (according to UniProt)

structure

[PDB|1R3U], from Caldanaerobacter subterraneus (39% identity)

[AF|P75119]

expression and Regulation

other regulations

expression is altered upon depletion of the [protein|84ec337a1f299161ee8f9778847bccbd3f07534d|Lon] protease [pubmed|33320415]

references

33320415

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Time of last update: 2025-04-11 13:43:09

Author of last update: Jstuelk