lon

M129

(protein(n) + ATP + H20 = peptide(n-m) + peptide(m) + ADP +Pi )n, reversible reaction

cytoplasm

Acetylated in Lysine, at K772 [pubmed|22373819]

Acetylated in Lysine, at K130 [pubmed|22373819]

differentially detected proteins upon [gene|84ec337a1f299161ee8f9778847bccbd3f07534d|lon] depletion (potential [protein|84ec337a1f299161ee8f9778847bccbd3f07534d|Lon] targets): [protein|0484c7bd82cb962ed3477df515514823cc75e0c0|HsdS-089], [protein|4d747a6690fe8fdebec528a02860bd201b26caa5|Mpn096], [protein|db34450e3c907d2f32237fea203dd8d4ad56204b|Mpn107], [protein|80a27e3aa65663a2a09893261b5d900fcfa3c0a5|Mpn108], [protein|6b75ac4d5fd003e6dc26fb8ec51940bd992bcbde|Mpn111], [protein|e5afe62f16041f0f37ddfd3dba13dc63864b0b04|Mpn139], [protein|3d1840b2bd4ff856c801dbba7de591100ebe8f7e|Mpn146], [protein|27d602d95201a28a4ed0c268743bd98301a335c4|Mpn199], [protein|d91739551b7211e882ab420d07f897ad0bd7e03c|HsdS-201], [protein|d14d49cc7c33cc3de966bb60e1e7149c27635e07|Mpn283], [protein|2855917faeaeb3da24481aa3d8bf853b6fbc5faa|HsdS-285], [protein|00626f3365851510bd1b8dd3f307d1ce7ea882df|HsdS-289], [protein|9ccb9eb9937041bd307879d967ec0aa78c274f04|ArcA-N], [protein|4dc1c2846c01a830250734cd4242f405dddc2731|Mpn333], [protein|af6c42f6211f11539fbc47284196da49c4fe6c41|BcrA], [protein|228e671668a623ea86033171bea1a7f125651bc5|Mpn335], [protein|60c5724b936a5f67ebe881c1cc10f1f910bec7cb|HsdS-343], [protein|21ce2cd1fdd442f37a0bcd25d50dc3c4b93c3115|Mpn347a], [protein|2d73894392334da724f25f2d923a606403407d11|Mpn347b], [protein|2e314b4b18ed4ec2ccff47ecf7ce9df060a9fa1e|Mpn365], [protein|ab8f9f75e1517aaeda2b7ff1ca6498e2ceb94f30|Mpn411], [protein|29b519bb484fc763772588716363da4a127237ee|Mpn458], [protein|f172a048c8bb4db056ef0dbf134bcea73ea431d7|UlaG], [protein|38c8e5ae7a5ef032de4bb96f18a61da3e0901030|Mpn508], [protein|d2b3a789b0f90a00cca6fe6f1bfc94cc02121bfe|Mpn514], [protein|cd600288fab0c704dd6698e9ce349f8e55f12b3e|DnaB], [protein|9be70592945683a9c7d464cbebd96942f6b08bb5|RrlB], [protein|1fd4f3d1b162c91fc6b3844439c9678b8cb9ca16|MucB], [protein|dd8691a6a765e90182f6ac9c71d21f05f7e95bbb|Mpn581], [protein|48339af05cc3465fc26cf887be58a552572f72e0|Mpn612], [protein|cb170fd628268ca0ea955e63388d9a10930a2ba8|HsdS-615] [pubmed|33320415]

differentially expressed proteins upon [gene|84ec337a1f299161ee8f9778847bccbd3f07534d|lon] depletion: [protein|988137a98226db9155d43edcaad602d1fb492dbd|Xdj1], [protein|c0593a19a3f217c46138addcd3632ceeae898213|Pmd1], [protein|9df4e76f4e71e1ed75dfb42ec6107dd70a21be60|TrsB], [protein|64f1d20cbde95aaefdb9baedb6591f9e97471c82|YfkM], [protein|83f370fb041d3a95574c8270256f9cb0fd336dc4|Tdk], [protein|a4e61cde64411cca46260ac72b4234e1260a66cf|Mpn145], [protein|3f92bd5158bdaaf9e5601426371ca5e3d1fbe01f|EcfA2], [protein|bf177e46980fb4ce4db525da752a6fa7256a890b|MglA], [protein|218ee95ba1f736be8e801f28a08d5bba681b285d|Mpn287], [protein|66a8357c2a518f35ee56d76c61dd1630bacc0c6d|RluD], [protein|3c8462847cd87cd50439e48cef42d7ba74d5eecf|AcpS], [protein|c1ace271c382d63e211550f7eb8d2b3a5c338212|MraW], [protein|22b98cf5d05de777f1c8beaadbdbca97f2502b7d|Mpn316], [protein|940ba462a5abfbe2ff63da09edebcda6a1bb5cac|FtsZ], [protein|81809542aaec542ce864adf4e839e80f5cebe409|MutB1], [protein|0c6f823397687e00ec29c24980145532d82ccc13|HsdM], [protein|3f95adb6a346c2cdb5b1dfb9b35ce63b2dab525a|Mpn368], [protein|2416c603e7ea02201d99045de5b09715fed56215|Mpn433], [protein|ad605db12abf19a55088dda503b16105dd1e7566|TrmB], [protein|b0f39240a3816c4fc1b6e78985323dc5602d578d|CshB], [protein|716b2228fbbfd9817963f377e3b1b082291761a8|Lip3], [protein|23b63bd5c95d348379320effe0b7c597f9fdfb6b|RecA], [protein|e4d585048dc983d67b7784030a946e165068b9d0|AraD], [protein|1769dc64ba7a321edaa79b3147693bdfe45a34bb|YqaJ], [protein|f178731de36b296f538f7954669a7741eedd876e|Adh], [protein|094aee4fccf95aedd644d063e0c22396e8a60ae5|RpmB], [protein|fbd4a69afe698c4661939580f20fa53776d83483|Mpn633], [protein|81523fd71b95f87bc1211a09b7b0d8a94b4dc8d7|Hpt] [pubmed|33320415]

[PDB|3M6A], from Bacillus subtilis, Crystal structure of Lon C-terminal domain (50% identity) [pubmed|20600124]

[AF|P78025]