dnaA

dnaA
M129

locus
MPN686
function
DNA replication
product
Chromosomal replication initiator protein dnaA
MW
48290
pI
9.33
Gene length
1320 bp Sequence Blast
Protein length
439 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0593

This gene is a member of the following regulons

gene
coordinates
814787 → 813468 (-)
the protein
catalyzed reaction/ biological activity
dnaA -ADP + ATP + ? = dnaA-ATP + ADP + ?, reversible reaction
dnaA -ATP + dsDNA = dnaA-ATP-dsDNA, reversible reaction
dnaA-ATP-dsDNA = dnaA-ADP + Pi + dsDNA, reversible reaction
localization
cytoplasm (according to UniProt)
modification
Acetylated in Lysine, at K108 [pubmed|22373819]
structure
[PDB|2HCB], from Aquifex aeolicus, Structure of AMPPCP-bound DnaA (33% identity) [pubmed|16829961]
[AF|Q59549]
references
reviews
20157337,21035377,21639790,22575476,22797751,26706151,28075389,30863373
original publications
16829961,32732422,22373819

8c1109c464f363574a5c164a377f1abcc5b340a2

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Time of last update: 2025-05-27 11:40:59

Author of last update: Jstuelk