nadD
M129
nicotinamide-nucleotide adenylyltransferase (NadD portion) combined with a function that repairs mistakes made by NadD (YqeK portion)
locus
MPN336
function
Vitamin/Folate metabolism
product
nicotinamide-nucleotide adenylyltransferase (NadD portion) combined with a function that repairs mistakes made by NadD (YqeK portion)
MW
37840
ec
2.7.7.18; 2.7.7.3; 2.7.7.15
pI
10.22
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1057, COG1713
This gene is a member of the following regulons
gene
coordinates
399392 → 398358 (-)
the protein
catalyzed reaction/ biological activity
choline phosphate + CTP = CDP-choline + pyrophosphate, reversible reaction
nicotinate D-ribonucleotide + ATP = deamido-NAD+ + PPi, reversible reaction
pantetheine 4'-phosphate + ATP = dephospho-CoA + PPi, reversible reaction
localization
cytoplasm
modification
Acetylated in Lysine, at K238 [pubmed|22373819]
Acetylated in Lysine, at K229 [pubmed|22373819]
structure
[PDB|2H29], from Staphylococcus aureus, Crystal structure of Nicotinic acid mononucleotide Adenylyltransferase: product bound form 1 (31% identity) [pubmed|16784754]
[AF|P75442]
references
Page visits: 139
Time of last update: 2024-05-06 14:23:57
Author of last update: Jstuelk