prpC

prpC
M129

locus
MPN247
function
Signal transduction
product
Putative protein phosphatase PrpC (EC 3.1.3.16)
MW
28490
ec
3.1.3.16
pI
8.58
synonyms
ptc1
Gene length
780 bp Sequence Blast
Protein length
259 aa Sequence Blast
essential
no
Outlinks
UniProt STRING PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0631

This gene is a member of the following regulons

gene
coordinates
298329 → 299108 (+)
phenotypes of a KO
11 genes changing
glided more than twice as frequently as wild-type cells [pubmed|31445891]
same behaviour as WT with glycerol [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
Protein-phosphoserine + H2O = Protein-serine + Pi + H+, reversible reaction
Protein-phosphothreonine + H2O = Protein-threonine + Pi + H+, reversible reaction
localization
cytoplasm
modification
Phosphorylated in Ser/Thr, at T29 [pubmed|22373819]
cofactors
Mg2+
Mn2+
structure
[PDB|6IHW], from Staphylococcus aureus, Crystal structure of bacterial serine phosphatase bearing R161K mutation (30% identity) [pubmed|30868877]
[AF|P75525]
references
30868877,21372323,20097688,19858294,23396910,16857667,31445891,22373819

a1871fe6981067230b57334318ed58a1a6e601c0

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Time of last update: 2024-12-17 01:09:50

Author of last update: Jstuelk