prs

prs
M129

phosphoribosylpyrophosphate synthetase, universally conserved protein

locus
MPN073
function
phosphoribosylpyrophosphate synthesis
product
phosphoribosylpyrophosphate synthetase
MW
37400
ec
2.7.6.1
pI
10.05
Gene length
1020 bp Sequence Blast
Protein length
340 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0462

This gene is a member of the following regulons

gene
coordinates
88091/87960 → 86925 (-)
the protein
catalyzed reaction/ biological activity
D-ribose 5-phosphate + ATP = 5-phospho-D-ribose 1-PPi + AMP, reversible reaction
localization
cytoplasm (according to UniProt)
structure
[PDB|1DKR] from Bacillus subtilis, Crystal structure of phosphoribosylpyrophosphate synthetase (43% identity) [pubmed|10742175]
[AF|P75044]
references
reviews
28031352
original publications
10742175

ba18828094c08986a9081366700af4ad2f3dc0f6

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Time of last update: 2024-04-28 19:16:49

Author of last update: Jstuelk