ptxA
M129
locus
MPN372
function
Pathogenesis
product
ADP-ribosylating toxin CARDS (EC 2.4.2.-) (CARDX TX) (ADP-ribosyltransferase CARDS)
MW
65010
ec
2.4.2.-
pI
5.85
synonyms
CARDS toxin
essential
no
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
gene
coordinates
444341 → 446116 (+)
the protein
catalyzed reaction/ biological activity
NAD-ADP-ribose + protein-(cys,asp,glu,lys,arg,asn) = NAD+ + protein-(cys,asp,glu,lys,arg,asn)-ADP-ribose, reversible reaction
localization
cell membrane [pubmed|16617115]
peripheral membrane protein [pubmed|16617115]
extracellular side [pubmed|16617115]
cell surface [pubmed|25139904]
modification
Acetylated in Lysine, at K520 [pubmed|22373819]
cofactors
NAD+
structure
[PDB|4TLW], from Mycoplasma pneumoniae, Adp-ribosylating Toxin Cards (100% identity) [pubmed|25848012]
[AF|P75409]
references
Page visits: 305
Time of last update: 2024-04-20 00:19:15
Author of last update: Jstuelk