lysS
M129

locus

MPN277

function

tRNA synthases

product

Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS)

53790

6.1.1.6

7.1

Gene length

1470 bp Sequence Blast

Protein length

489 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1190

This gene is a member of the following regulons

gene

coordinates

326856 → 328325 (+)

the protein

catalyzed reaction/ biological activity

L-lysine + tRNA(Lys) + ATP = L-lysyl-tRNA(Lys) + AMP + PPi, reversible reaction

ATP + ATP = ApppA + 2(Pi), reversible reaction

localization

cytoplasm (according to UniProt)

structure

[PDB|3A74], from Geobacillus stearothermophilus, Lysyl-tRNA synthetase complexed with Diadenosine Tetraphosphate (AP4A) (48% identity)

[AF|P75500]

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Time of last update: 2024-04-28 07:29:43

Author of last update: Sojhi