tklB
M129
Transketolase
locus
MPN082
function
Pentose phosphate pathway
product
transketolase
MW
71280
ec
2.2.1.1
pI
7.59
essential
conditional essential
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
101985 → 103931 (+)
phenotypes of an overexpression
Fast growth and slow acidification [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate = D-xylulose 5-phosphate + D-erythrose 4-phosphate, reversible reaction
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate, reversible reaction
localization
cytosol [pubmed|26667841]
membrane [pubmed|26667841]
modification
Acetylated in Lysine, at K641 [pubmed|22373819]
Acetylated in Lysine, at K306 [pubmed|22373819]
Acetylated in Lysine, at K133 [pubmed|22373819]
Acetylated in Lysine, at K259 [pubmed|22373819]
cofactors
TTP, Mg2+
structure
[PDB|4C7V] from Lactobacillus salivarius, Apo Transketolase at 2.2A resolution (38% identity) [pubmed|26457526]
[AF|P75611]
references
reviews
original publications
Page visits: 132
Time of last update: 2024-04-29 01:15:54
Author of last update: Jstuelk