trxB
M129

locus

MPN240

function

Nucleotide metabolism/Salvage + Redox balance

product

Thioredoxin reductase (TRXR) (EC 1.8.1.9)

34650

1.8.1.9

7.23

Gene length

948 bp Sequence Blast

Protein length

315 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0492

This gene is a member of the following regulons

gene

coordinates

292328 → 293275 (+)

the protein

catalyzed reaction/ biological activity

txrB-R'-S-S-R' + NADPH + H+ = trxB-(R´-SH)2 + NADP+, reversible reaction

localization

cytoplasm (according to UniProt)

cofactors

FAD

structure

[PDB|5UWY], from Streptococcus pyogenes, The crystal structure of thioredoxin reductase (40% identity)

[AF|P75531]

references

32732422,23899494,35862786

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Time of last update: 2024-10-27 11:38:12

Author of last update: Jstuelk