parC
M129
locus
MPN123
function
chromosome segregation and compaction
product
subunit of DNA topoisomerase IV
MW
86790
ec
5.99.1.-
pI
9.35
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
158374 → 160743 (+)
the protein
catalyzed reaction/ biological activity
a double stranded positively supercoiled DNA + ATP = relaxed double stranded DNA + ADP + Pi, reversible reaction
localization
cell membrane, peripheral membrane protein, chromosome, extrinsic component of plasma membrane (according to UniProt)
modification
Acetylated in Lysine, at K458 [pubmed|22373819]
structure
[PDB|4I3H] the [protein|525c6dc24571fb58d491bef41af12c5efdf17642|ParE]-[protein|c6dc466d813dc45f428990be395f7addd6dffd57|ParC] complex of Streptococcus pneumoniae (49% identity) [pubmed|23965305]
[AF|P75352]
references
reviews
original publications
Page visits: 255
Time of last update: 2024-04-29 18:20:44
Author of last update: Jstuelk