ptsH
M129
HPr, General component of the sugar phosphotransferase system (PTS)
locus
MPN053
function
PTS-dependent sugar transport and phosphorylation
product
PTS phosphocarrier protein HPr
MW
9680
ec
2.7.11.-
pI
9.13
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
66822 → 67088 (+)
phenotypes of an overexpression
same behaviour as WT with glycerol [pubmed|31445891]
phenotypes of a mutant
same behaviour as WT with glycerol [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
MtlR + HPr ↔ MtlR-HPr, reversible reaction
phosphoenolpyruvate + HPr ↔ pyruvate + HPr-Phis, reversible reaction
PtsI-Phis + HPr ↔ HPr-Phis + PTS enzyme I, reversible reaction
localization
cytoplasm (according to UniProt)
modification
Acetylated in Lysine, at K84 [pubmed|22373819]
Acetylated in Lysine, at K65 [pubmed|22373819]
Acetylated in Lysine, at K30 [pubmed|22373819]
Phosphorylated in Ser/Thr, at S47, by [protein|f8a1c2adaa1406d1bcb2d096d53f26c93d193857|HprK] [pubmed|22373819]
structure
[PDB|1PCH] from Mycoplasma capricolum, Histidine-containing phosphocarrier protein (44% identity) [pubmed|7582895]
[AF|P75061]
references
reviews
original publications
Page visits: 635
Time of last update: 2024-05-10 22:54:24
Author of last update: Jstuelk