glpO
M129
Glycerol-3-phosphate oxidase, generates the virulence factor H2O2
locus
MPN051
function
utilization of glycerol and lipids
product
glycerol-3-phosphate oxidase
MW
42240
ec
1.1.99.5; 1.1.3.21
pI
9.32
synonyms
glpD
essential
no
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
64648 → 63494 (-)
phenotypes of a KO
Slow acidification [pubmed|31445891]
Slow growth [pubmed|31445891]
no H2O2 production with glycerol [pubmed|19028882]
reduced pathogenicity [pubmed|19028882]
more resistant to glycerol growth inhibition [pubmed|31445891]
phenotypes of an overexpression
Slow acidification
the protein
catalyzed reaction/ biological activity
2 D-glycerol 3-phosphate + O2 = 2 glycerone phosphate + H2O2, reversible reaction
localization
SignalP
modification
Acetylated in Lysine, at K130 [pubmed|22373819]
Acetylated in Lysine, at K64 [pubmed|22373819]
Acetylated in Lysine, at K290 [pubmed|22373819]
Acetylated in Lysine, at K298 [pubmed|22373819]
Acetylated in Lysine, at K368 [pubmed|22373819]
structure
[PDB|4X9M] from Mycoplasma pneumoniae, Oxidized L-alpha-glycerophosphate oxidase with FAD bound (100% identity) [pubmed|25688572]
[AF|P75063]
references
reviews
original publications
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Time of last update: 2025-04-29 00:49:48
Author of last update: Jstuelk