spxA

spxA
M129

transcription regulator Spx

locus
MPN266
function
Transcription factors
product
transcription regulatory protein Spx
MW
15950
ec
1.20.4.1
pI
10.41
Gene length
438 bp Sequence Blast
Protein length
145 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1393

This gene is a member of the following regulons

gene
coordinates
318144 → 318581 (+)
phenotypes of a KO
slow growth [pubmed|31445891]
slow acidifcation [pubmed|31445891]
more sensitive to glycerol inhibition of growth [pubmed|31445891]
the protein
localization
cytoplasm
modification
Acetylated in Lysine, at K45 [pubmed|22373819]
Acetylated in Lysine, at K129 [pubmed|22373819]
structure
[PDB|1Z3E], from Bacillus subtilis, Crystal structure of the anti-alpha, global transcriptional regulator, Spx, in complex with the {alpha} C-terminal domain of RNA polymerase (37% identity) [pubmed|16249335]
[AF|P75509]
references
reviews
19575568,20626317
original publications
32732422,19580872,16249335,23813734,22307755,15659166,12642660,18687074,16740936,20084284,20057163,10913081,23894131,23934352,22582280,24417481,24942655,25353645,25433860,28484046,31445891,22373819

ec39c334a522907336da562ae7c627510fe084c0

Page visits: 394

Time of last update: 2024-03-23 15:11:37

Author of last update: Jstuelk