fba
M129
fructose 1,6-bisphosphate aldolase, glycolytic enzyme
locus
MPN025
function
enzyme in glycolysis
product
fructose 1,6-bisphosphate aldolase
MW
31680
ec
4.1.2.13
pI
6.9
synonyms
tsr, fba
essential
yes
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
gene
coordinates
30244 → 31110 (+)
the protein
catalyzed reaction/ biological activity
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate, reversible reaction
D-fructose 1-phosphate = glycerone phosphate + D-glyceraldehyde, reversible reaction
localization
cytosol [pubmed|26667841]
modification
Acetylated in Lysine, at K256 [pubmed|22373819]
Acetylated in Lysine, at K248 [pubmed|22373819]
Acetylated in Lysine, at K54 [pubmed|22373819]
Acetylated in Lysine, at K165 [pubmed|22373819]
Acetylated in Lysine, at K256 [pubmed|22373819]
Phosphorylated in Ser/Thr, at T231 [pubmed|22373819]
Phosphorylated in Ser/Thr, at ATNLPLVLHGGpSGIPEADVK [pubmed|22373819]
Phosphorylated in Ser/Thr, at S47/ T48/ S49 [pubmed|22373819]
cofactors
Zn2+
structure
[PDB|4TO8] from ''Staphylococcus aureus'', a Fructose 1,6-bisphosphate aldolase (46% identity) [pubmed|25390935]
[AF|P75089]
references
reviews
original publications
Page visits: 146
Time of last update: 2025-04-10 12:25:56
Author of last update: Jstuelk