prkC

prkC
M129

locus
MPN248
function
Signal transduction
product
Putative serine/threonine-protein kinase PrkC (EC 2.7.11.1)
MW
42790
ec
2.7.11.1
pI
9.53
Gene length
1170 bp Sequence Blast
Protein length
389 aa Sequence Blast
essential
no

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0515

This gene is a member of the following regulons

gene
coordinates
299099 → 300268 (+)
phenotypes of a KO
42 genes changing [pubmed|31445891]
non-adherent growth [pubmed|19858294]
no cytotoxicity, glided at approximately half the frequency of wild-type cells [pubmed|31445891]
same behaviour as WT with glycerol [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
Protein-serine + ATP = Protein-phosphoserine + ADP, reversible reaction
Protein-threonine + ATP = Protein-phosphothreonine+ ADP, reversible reaction
localization
membrane-internal
cofactors
Mg2+
structure
[PDB|4EQM], from Staphylococcus aureus, Structural analysis of serine/threonine kinase PknB (29% identity) [pubmed|22701750]
[AF|P75524]
references
22701750,32732422,21372323,20097688,19858294,22373819,23396910,31445891

f509c1e951bb17604c3bfcd5af69fb9655916c48

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Time of last update: 2024-12-21 17:48:31

Author of last update: Jstuelk