hprK

hprK
M129

[protein|df45c8bdce577e60a6e0724c93b1c9699542d1f3|HPr] kinase (HPrK), regulatory phosphorylation of [protein|df45c8bdce577e60a6e0724c93b1c9699542d1f3|HPr]

locus
MPN223
function
control of PTS activity and sugar uptake
product
[protein|df45c8bdce577e60a6e0724c93b1c9699542d1f3|HPr] kinase (HPrK)
MW
34320
ec
2.7.11.-; 2.7.4.-
pI
9.27
Gene length
939 bp Sequence Blast
Protein length
312 aa Sequence Blast
essential
no
Outlinks
UniProt STRING PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1493

This gene is a member of the following regulons

gene
coordinates
274571 → 275509 (+)
phenotypes of a KO
slow growth [pubmed|31445891]
same behaviour as WT with glycerol [pubmed|31445891]
phenotypes of an overexpression
fast growth [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
[protein|df45c8bdce577e60a6e0724c93b1c9699542d1f3|HPr]-serine46 + ATP --> [protein|df45c8bdce577e60a6e0724c93b1c9699542d1f3|HPr]-phosphoserine46 + ADP, [pubmed|12368461]
localization
cytoplasm
cofactors
Mg2+
effectors of protein activity
Glycerol
structure
[PDB|1KNX] [pubmed|12589763]
[AF|P75548]
biological materials
mutant
GPM51 (hrpK::mini-Tn10, Gmr) [pubmed|16857667]
references
reviews
12837773,15023355,18628769
original publications
15547265,15927419,16857667,11856840,12368461,12589763,14717704,12589763,20097688,31445891

f8a1c2adaa1406d1bcb2d096d53f26c93d193857

Page visits: 639

Time of last update: 2025-06-24 20:37:37

Author of last update: Jstuelk