hit1
M129

locus

MPN273

function

Signal transduction

product

Diadenosine tetraphosphate Ap4A hydrolase (EC 3.6.1.41)

15840

3.6.1.41

7.13

Gene length

435 bp Sequence Blast

Protein length

144 aa Sequence Blast

essential

yes

Outlinks

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0537

This gene is a member of the following regulons

gene

coordinates

324889 → 324455 (-)

phenotypes of an overexpression

57 genes changing [pubmed|31445891]

the protein

catalyzed reaction/ biological activity

ApppA + H2O = 2 ADP, reversible reaction

localization

cytoplasm

modification

Acetylated in Lysine, at K67 [pubmed|22373819]

structure

[PDB|1Y23], from Bacillus subtilis, Crystal structure of a member of HIT family of proteins (49% identity)

[AF|P75504]

references

32732422,31445891,22373819

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Time of last update: 2024-12-15 03:09:49

Author of last update: Jstuelk