hit1

hit1
M129

locus
MPN273
function
Signal transduction
product
Diadenosine tetraphosphate Ap4A hydrolase (EC 3.6.1.41)
MW
15840
ec
3.6.1.41
pI
7.13
Gene length
435 bp Sequence Blast
Protein length
144 aa Sequence Blast
essential
yes

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0537

This gene is a member of the following regulons

gene
coordinates
324889 → 324455 (-)
phenotypes of an overexpression
57 genes changing [pubmed|31445891]
the protein
catalyzed reaction/ biological activity
ApppA + H2O = 2 ADP, reversible reaction
localization
cytoplasm
modification
Acetylated in Lysine, at K67 [pubmed|22373819]
structure
[PDB|1Y23], from Bacillus subtilis, Crystal structure of a member of HIT family of proteins (49% identity)
[AF|P75504]
references
32732422,31445891,22373819

b5e12dfd63401cb43dcb7b4a02f0366685f86d06

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Time of last update: 2024-05-19 23:12:03

Author of last update: Jstuelk